The First Blast of the Trumpet Against the Monstrous Regiment of Women (1558) may be the most misogynistic screed ever written:
For who can denie but it is repugneth to nature, that the blind shall be appointed to leade and conduct such as do see? That the weake, the sicke and impotent persons shall norishe and kepe the hole and strong? And finallie, that the foolishe, madde and phrenetike shal governe the discrete and give counsel to such as be sober of mind. And such be al women, compared unto man in bearing of authoritie. For their sight in civile regiment is but blindness; their strength, weaknes; their counsel, foolishnes; and judgment, phrensie, if it be rightlie considered.
That’s ironic, because the author’s real beef was religious: John Knox opposed female sovereigns like Mary, Queen of Scots, and Mary Tudor because of their Catholicism. When Elizabeth Tudor succeeded Mary, his plan backfired — she was sympathetic to his cause, but offended at his words. Hell hath no fury.