Hugh “One-Arm” Daily lost his left arm in a gun accident but went on to win 73 games as a professional pitcher between 1882 and 1887, including a no-hitter.
Mordecai “Three-Finger” Brown (above) lost two fingers in farm machinery as a boy but pitched for 13 seasons between 1903 and 1916, finishing with 1,375 strikeouts.
Pete Gray lost his right arm in a wagon accident but played briefly for the St. Louis Browns in 1945, fielding with a glove but transferring the ball to his bare hand to throw.
A reporter once asked Brown whether lacking a finger made it harder to pitch. “Don’t know,” he said. “Never done it the other way.”