Section 3 of the 25th amendment permits a U.S. president to transfer his authority voluntarily to his vice president when he is “unable to discharge the powers and duties of his office.”

To date it’s been invoked only three times — in 1985 George H.W. Bush served as acting president while surgeons removed a cancerous polyp from Ronald Reagan’s colon, and in 2002 and 2007 Dick Cheney served while George W. Bush underwent colonoscopies.

So, to date, Section 3 has been invoked only for colon issues. Write your own joke.