In 1999, a letter in New Scientist noted that randomizing letters in the middle of words has little or no effect on readers’ ability to understand text. Noam D. Plum responded with a poem:

The suggetsoin taht chrilden slhuod laern how to sepll
Is a tmie-watse we ohgut to rjeect.
Sicne a jlumbe of leertts raeds pertlecfy wlel
If the frist and the lsat are crrocet.

Wehn an edtoir grembuls, “Yuor seplinlg is ntus!”
Wtih cntoempt he can braley cocneal,
Trehe is no cuase to flcnih; mkae no ifs adns or btus;
Say, “I’ts radnom, sir. Wa’hts the big dael?”

In tihs fsat-minvog wrold, waht we raed dseon’t sictk.
Olny vrey few deliats get strsseed.
If i’ts frsit or it’s lsat we may glncae at it qucik.
Woh’s got tmie to be raenidg the rset?

(Noam D. Plum, “Prepopr Splelnig,” Verbatim 32:1 [Spring 2008], 15. See Half Measures.)