In the 1890s, Waldemar Haffkine worked valiantly to develop vaccines against both cholera and bubonic plague. Then an unjust accusation derailed his career. In this week’s episode of the Futility Closet podcast we’ll describe Haffkine’s momentous work in India, which has been largely overlooked by history.
We’ll also consider some museum cats and puzzle over an endlessly energetic vehicle.
It is a traditional axiom of medicine that health is the absence of disease. What is a disease? Anything that is inconsistent with health. If the axiom has any content, a better answer can be given. The most fundamental problem in the philosophy of medicine is, I think, to break the circle with a substantive analysis of either health or disease.
In 1938, Italian physicist Ettore Majorana vanished after taking a sudden sea journey. At first it was feared that he’d ended his life, but the perplexing circumstances left the truth uncertain. In this week’s episode of the Futility Closet podcast we’ll review the facts of Majorana’s disappearance, its meaning for physics, and a surprising modern postscript.
We’ll also dither over pronunciation and puzzle over why it will take three days to catch a murderer.
Statistics textbooks sometimes ask: Suppose you’re driving on the highway and adjust your speed so that the number of cars you pass is equal to the number that pass you. Is your speed the median or the mean speed of the cars on the highway?
The expected answer is that it’s the median speed, since the number of cars traveling more slowly than you is equal to the number traveling faster. But California State University mathematician Larry Clevenson and his colleagues wrote in 2001, “This certainly is true of the cars that you see, but that isn’t what the problem asks, and it isn’t the correct answer.”
Surprisingly, they found that the correct answer is the mean. “If you adjust your speed so that as many cars pass you as you pass, then your speed is the mean speed of all the other cars on the highway.” Details at the link below.
Temple University anthropologist Wayne Zachary was studying a local karate club in the early 1970s when a disagreement arose between the club’s instructor and an administrator, dividing the club’s 34 members into two factions. Thanks to his study of communication flow among the members, Zachary was able to predict correctly, with one exception, which side each member would take in the dispute.
The episode has become a popular example in discussions of community structure in networks, so much so that scientists now award a trophy to the first person to use it at a conference. The original example is known as Zachary’s Karate Club; the trophy winners are the Zachary’s Karate Club Club.
09/01/2024 Reader Peter Dawyndt points out that the reason for the single exception in Zachary’s prediction is notable. The person whom Zachary assigned to the wrong faction corresponds to node 9 in this graph of the network:
“This person joined the newly founded karate club with supporters of the teacher (node 1) after the split, despite being a weak supporter of the president (node 34). This choice stemmed mainly from opportunism: he was only three weeks away from a test for black belt (master status) when the split in the club occurred. Had he joined the president’s club, he would have had to give up his rank and begin again in a new style of karate with a white (beginner’s) belt, since the president had decided to change the style of karate practiced in his club. Having four years of study invested in the style of the original club’s instructor, the individual could not bring himself to repudiate his rank and start again.”
This cottage, at 112 Mercer Street in Princeton, New Jersey, has been home to three Nobel winners: Albert Einstein lived there from 1935 to 1955; physicist Frank Wilczek between 1989 and 2001; and economist Eric Maskin until 2012.
It resides on the National Register of Historic Places and has been designated a U.S. National Historic Landmark, but it bears no outward marker of its significance.
“Quantities of liquid expressed in gallons, pottles, quarts, pints, etc. were essentially written in binary notation,” Knuth writes. “Perhaps the true inventors of binary arithmetic were British wine merchants!”
What most clinicians do when they receive a laboratory report is, of course, to look up the normal range for the tests in question. … Traditionally, a normal range is calculated in such a way that it includes 95% of the results found in a group of normal or healthy persons, and, consequently, there is a 5% risk that a healthy person will present with an abnormal laboratory result. Then, imagine that you do ten tests on a normal person. In that case the risk that at least one of these tests is abnormal is (1 – 0.9510) which amounts to 0.40 or 40%. If you do twenty-five tests (and that is not uusual in clinical practice), this chance is 72%! As Edmond A. Murphy puts it so aptly, ‘Therefore, a normal person is anyone who has not been sufficiently investigated.’
— Henrik R. Wulff, Stig Andur Pedersen, and Raben Rosenberg, Philosophy of Medicine: An Introduction, 1990, citing Murphy’s The Logic of Medicine, 1976
Spiders are largely blind but experience the world through vibrations in their webs, which they detect with their legs. Now MIT materials scientist Markus Buehler has created a musical impression of that experience. His team made three-dimensional maps of the webs of tropical tent-web spiders, identified the vibrating frequency of each thread, and converted these frequencies into ranges that humans can hear. Threads that are closer to the spider sound louder in the recording.
“The spider web can be viewed as an extension of the body of the spider, in that it lives within it, but also uses it as a sensor,” Buehler told New Scientist. “When you go into the virtual reality world and you dive inside the web, being able to hear what’s going on allows you to understand what you see.”